Regional Center for Prophylaxis and Control of AIDS and Infectious Diseases, Lipetsk; Ivanovsky Research Institute of Virology, Moscow, Russia
Molecular epidemiologic study of HIV-1 variants isolated in the Lipetsk region during 1994 — 2006 period was performed. It has been shown that 3 env-subtypes (A, B, and C) and 3 gag-subtypes (A, B, and C) are widespread in the region. The virus was transmitted both sexually and by injecting drug users. Phylogenetic analysis of gag and env genes nucleotide sequences was performed, which revealed that 4 variants of HIV-1 with genotypes gagA/envA, gagB/envB, gagC/envC, and recombinant gagA/envB are circulating in the region.
Zh. Mikrobiol. (Moscow), 2007, No. 3, P. 77—81