nstitute of Marine Biology; Pacific Institute of Bioorganic Chemistry, Vladivostok; Central Research Institute of Epidemiology, Moscow, Russia
The study showed that κ/λ-carrageenan increase non-specific resistance to impact of Escherichia coli lypopolysaccharide (LPS)-induced endotoxinemia in mice. Carrageenan was administered intragastrically in dose 100 mg/kg/day during 5 days followed by intraperitoneal injection of LPS in dose 1 mg/kg. Carrageenan hampered the involution of thymus, hypertrophy of adrenal glands, the changes on level of thyroid hormones and corticosterone in serum, the activation of glycogenolysis, glycolysis, and peroxidation of lipids in liver.
Zh. Mikrobiol. (Moscow), 2007, No. 2, P. 57—60