Menshikova, E.A., Podosinnikova, L.S., Mironova, A.V., Salnikova, O.I.

Hemolytic activity and toxigenicity of Vibrio cholerae of different serogroups

Research Institute for Plague Control, Rostov-on-Don, Russia

Experimental data on the comparative evaluation of the hemolytic activity of ctx⁺ Hly‾ and ctx‾ Hly⁺ V.cholerae, serogroups O1 and O139, in the process of their cultivation in different nutrient media are presented. The capacity of ctx⁺ V.cholerae of both serogroups cultivated under the conditions of iron deficiency, for the production of hemolysin capable of lyzing sheep red blood cells was shown. Hemolysin produced by ctx‾ strains of V.cholerae was synthesized under any conditions. The study of hemolysin preparations obtained from ctx‾ and ctx⁺ strains of V. choleae, serogroups O1 and O139, revealed that they were biologically and immunologically similar.
Zh. Mikrobiol. (Moscow), 2002, No. 5, P. 7—11