Ryapis, L.A., Briko, N.I., Dmitrieva, N.F., Eshchina, A.S., Pronsky, A.V., Filatov, N.N., Ivanenko, A.V., Salova, N.Ya., Sizykh, E.V., Pavlovsky, S.S., Skorkina, Yu.A., Trofimov, D.Yu., Kirillov, M.Yu., Sobolev, V.I.

Complex typing of group A streptococci isolated from different social and age groups of population

Sechenov Medical Academy, Center of Hygiene and Epidemiology, Scientific-production association “DNA-Technology”, Moscow, Russia

Pulse-electrophoresis, sequencing of emm genes coding protein M and PCR analysis of speA, speB, and speC genes were used for characterization of group A streptococci (GAS) isolated in different years in Moscow and Tuapse mostly from children and military staff. It has been shown that epidemic process of streptococcal infection caused by GAS in Moscow is based on circulation of many independent clones of Streptococcus pyogenes. Obtained data on complex typing of S.pyogenes would be useful for study of molecular epidemiology of diseases caused by GAS and improvement of epidemiologic surveillance.
Zh. Mikrobiol. (Moscow), 2007, No. 1, P. 30—34