Research Institute for Plaque Control of Siberia and Far East, Irkutsk, Russia
Genotypic characteristics based three main factors of pathogenicity (presence of resident plasmids [pYV, pVM], gene of toxin-superantigen ypm and nine genes for high pathogenicity island [HPI]) of 212 strains of Y.pseudotuberculosis isolated in Siberia and Far East were studied. It was shown that strains of Y.pseudotuberculosis with one of two variants of plasmids 82:47 MDa and 47 MDa (60,8% and 31,6% respectively) are predominated. Gene ypmA was detected in 96,2% of isolated strains. Eight strains had none of the ymp gene variants. HPI were detected in 96,2% of isolated strains. Obtained characteristics of Y.pseudotuberculosis allowed to determine the dominating genogroup pYV+, ypmA+, HPI- (95,8% of strains) that cause systemic infection.
Zh. Mikrobiol. (Moscow), 2006, No. 6, P. 20—25