Lyashchuk, A.M., Lunin, V.G., Karyagina, A.S., Lavrova, N.V., Rodionova, I.V., Kormilitsina, M.I., Meshcheryakova, I.S., Verkhovskaya, L.V., Naroditsky, B.S., Gintsburg, A.L.

Immunization with cellulose — immobilized antigens. The development of A.E.Gurvitch concept

Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia

A highly purified TUL4-CBD chimeric protein was obtained by one stage purification method. TUL4-CBD protein consists of TUL4 Francisella tularensis mature peptide sequence, Gly-Ser spacer and cellulose binding domain (CBD) of Anaerocellum thermophilum. The TUL4-CBD protein was shown to induce production of specific antibodies to TUL4 protein in laboratory animals.
Zh. Mikrobiol. (Moscow), 2006, No. 4, P. 65—68

Lyashchuk, A.M., Lunin, V.G., Karyagina, A.S., Lavrova, N.V., Rodionova, I.V., Kormilitsina, M.I., Meshcheryakova, I.S., Verkhovskaya, L.V., Naroditsky, B.S., Gintsburg, A.L.Immunization with cellulose — immobilized antigens. The development of A.E.Gurvitch concept

Lyashchuk, A.M., Lunin, V.G., Karyagina, A.S., Lavrova, N.V., Rodionova, I.V., Kormilitsina, M.I., Meshcheryakova, I.S., Verkhovskaya, L.V., Naroditsky, B.S., Gintsburg, A.L.

Immunization with cellulose — immobilized antigens. The development of A.E.Gurvitch concept