Kartashova, O.L., Kirghizova, S.B., Stadnikov, A.A., Shevlyuk, N.N., Kovbyk, L.V., Chuenko, E.A.

Anticarnosine activity of staphylococci as a criterion for assessment of their persistence potentia

Institute for Cellular and Intracellular Symbiosis, State Medical Academy, Orenburg, Russia

The analysis on clinical material and the use of experimental models allowed to prove the role of anticarnosine activity of staphylococci in their persistence. Light and electronic microscopy revealed large destruction of ultrastructural eukaryote components and decreased proliferative activity in animals challenged with strains characterized by high anticarnosine activity. Adaptive mechanisms, providing dynamic equilibrium in “eukaryote — prokaryote” system, are described.
Zh. Mikrobiol. (Moscow), 2006, No. 4, P. 13—16