Smolina, T.P., Chernyh, S.V., Gorshkova, R.P., Nazarenko, E.L.

The decrease of adhesion of microorganisms on the uroepitelium cells by polysaccharide isolated from marine proteobacterium Pseudoalteromonas nigrifaciens

Research institute of Epidemiology and Microbiology, Pacific Institute of Bioorganic Chemistry, Vladivostok, Russia

10 strains S.epidermidis, 6 strains S.aureus, 4 strains S.haemolyticus, 3 strains Micrococcus spp., 4 strains Enterobacter spp. and 4 strains Acinetobacter spp. were isolated from urethra patients with nonspecific urethritis. The adhesive activity of these bacteria to the human erythrocytes and uroepitheliocytes of healthy donors was determined. The level of adhesion on urethra epitheliocytes for all bacteria species except for Enterobacter spp. was in 2 — 15 times higher than on human erythrocytes. It was established that the polysaccharide isolated from P.
igrifaciens type strain IAM 13010T after incubation with S.aureus, S.epidermidis, S.haemolyticus and Acinetobacter spp. decreased the adhesion of these bacteria on human erythrocytes and uroepithelium cells.
Zh. Mikrobiol. (Moscow), 2006, No. 3, Supplement, P. 58—61