Nikitina,V.E., Bugaeva,I.O., Ponomareva,E.G., Tikhomirova,E.I., Bogomolova,N.V.

Influence of Azospirillium brasilense lectin on the kinetics of cell populations in mesenterial lymph nodes and the dynamics of the cytokine status of experimental animals

Institute of Biochemistry and Physiology of Plants and Microorganisms, State Medical University, Chernyshevsky State University, Saratov

The complex study of the influence of A.brasilense Sp 7 lectin with carbohydrate specificity to L-fucose and D-galactose on the dynamics of cell populations in different structural functional zones of the white mice mesentery, as well as on the capacity of immunocompetent cells of mesenterial lymph nodes for synthesizing cytokines (interleukin-1, interleukin-6 and tumor necrosis factor), was carried out. A single oral administration of bacterial lectin in a dose of 4.5 mg produced a pronounced immunostimulating effect.
Zh. Mikrobiol. (Moscow), 2002, No. 1, P. 37—42