Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia
H.influenzae non-typed strains cause diseases of respiratory organs, otitis, sinusitis and conjunctivitis. H.influenzae surface antigens play an important role in the vital activity of bacteria and the pathogenesis of diseases. A large number of antigens with similar functions and different structure, as well as the variability of their structure, determine the strain specificity of immune response and facilitate the development of chronic diseases. Modern data on the structure and functions of surface antigens of H.influenzae non-typed strains are presented.
Zh. Mikrobiol. (Moscow), 2006, No. 3, P. 113—120