Ivanovsky Research Institute of Virology, Moscow, Russia
Own results and literature data under the analysis of variability of a influenza virus A and population interactions in biological system: influenza virus À — wild and domestic animals — human are presented. Opportunities of virus reassortants appearance between viruses of animals and viruses of human and spreading the new pandemic variants are proved, in particular, at simultaneous infection of pigs with virus Í5 and viruses of human influenza Í1 and Í3, circulating worldwide. Blocks of preparation to a flu pandemic, including on vaccine prophylactic are stated. It is discussed, what vaccines it is necessary to prepare. Inadmissibility the use of alive influenza vaccines is emphasized.
Zh. Mikrobiol. (Moscow), 2006, No. 3, P. 96—100