Kurtasova, L.M., Ruzaeva, L.A., Dvoekonko, A.A., Opeikina, N.N., Shakina, N.A., Yashchenko, S.V., Zaryanko, G.A., Tretyakova, V.A., Fedotova, N.A.

Clinical and immunological effect of vaccination against Haemophilus imfluenzae, type b, in children with lesions of the nervous system

State Medical Academy, Territorial Center for Prophylaxis and Control of AIDS and Infectious Diseases, Moscow, Russia

Observations on 277 children aged 3 months to 4 years with lesions of the nervous system, immunized with vaccine Act-HIB (Aventis Pasteur, France), were carried out in groups of children. The significant decrease of the level of Hib nasopharyngeal carrier state in 3.3 times and the decrease of total morbidity in acute infections of respiratory and ENT organs in 2.7 times occurred after immunization was revealed. The immunological effect of immunization on the level of protective titers against H. influenzae, type b, in children with organic CNS lesions in children was shown.
Zh. Mikrobiol. (Moscow), 2006, No. 1, P. 25—28