Sarsenbaeva, A.S.

Specific features of Helicobacter pylori infection and the character of immune response in patients with a severe course of duodenal ulcer

Urals State Academy of Advanced Medical Training, Chelyabinsk, Russia

The presence of genetic markers of vacA-positive strains with s1/s2 subtype (76%) with a high proportions(84%)of mixed genotype and detection in a breath air the ammonia at significantly high concentrations, have been found to be the specific features of H. pylori infection in patients with a severe course of duodenal ulcer. A low level of specific IgG antibodies, the growth of immunological inflammation markers and the depression of humoral immunity have been established.
Zh. Mikrobiol. (Moscow), 2005, No. 6, P. 73—75