Institute of Immunology, Tashkent, Uzbekista
nThe content of total IgE in 109 patients at different stages of HIV infection are presented. The infection was at the asymptomatic stage in 30 patients, the stage of generalized lymphadenopathy in 29 patients, the stage of secondary manifestations in 36 patients, the stage of AIDS in 14 patients. The concentration of IgE was found to increase, on the average, at all stages of HIV infection (p<0.001), the maximum level being observed at the stage of AIDS. The occurrence of high and low concentrations of total IgE was the same at the asymptomatic stage and the stage of generalized lymphadenopathy. At the stage of secondary manifestations the occurrence of low concentrations of IgE increased twofold. In the presence of parasitosis a significant rise in the content of total IgE was registered in HIV-infected patients.
Zh. Mikrobiol. (Moscow), 2005, No. 5, P. 99—101