Popov, V.F., Yunasova, T.N., Gaiderova, L.A., Aksenov, L.A., Averina, O.B., Shitikova, O.Yu.

Characterization of antirubella vaccine in an epidemiological trial

Tarasevich State Research Institute for Standardization and Control of Medical Biological Preparations, Main State Sanitary and Epidemiological Surveillance Center of the Federal Head Office for Medico-Biological and Extreme Problems, Moscow, Russia

The work was aimed at the evaluation of the antigenic activity and reactogenicity of antirubella vaccine, manufactured by the Serum Institute of India, on the basis of the active observation of 373 children. Vaccinal reactions were registered in 8.8% of the vaccinees. Seroconversion after the injection of the vaccine was 100%. The results of the epidemiological trial demonstrated that the Indian antirubella vaccine was faintly reactogenic and had high antigenic activity.
Zh. Mikrobiol. (Moscow), 2004, No. 6, P. 41—43