Kuznetsov, V.G.

Method for the calculation of the 50% effective dose of biologically active agents

Research Institute of Epidemiology and Microbiology, Vladivostok, Russia

A newly proposed method for the mathematical and graphic determination and calculation of ED₅₀ (LD₅₀) on the abscissa at the meeting point of the cumulate of dead and the cumulate of survived animals (in absolute figures) in “dose — effect” experiments is described. “The method of meeting cumulates” for the calculation of ED₅₀ (LD₅₀) is simple, eliminates u

ecessary calculations, yields results, highly similar (95-100%) to those obtained by other methods and may be used in different medico-biological studies.
Zh. Mikrobiol. (Moscow), 2004, No. 6, P. 18—22