Bukharin, O.V., Kirillov, V.A.

On some mechanisms of the persistence of Helicobacter pylori

Institute of Cellular and Intracellular Symbiosis of the Urals Branch of the Russian Academy of Sciences, Orenburg, Russia

The mechanisms of the pathogenesis of Helicobacter pylori infection, ensuring the prolonged survival of these bacteria in the aggressive medium (gastric mucosa), are considered. A new approach to the systematization of the mechanisms of H.pylori persistence is proposed: the mechanisms ensuring the stability of H.pylori in the presence of aggressive physical and chemical factors, the mechanisms ensuring antagonistic effects in biocenosis and the mechanisms ensuring resistance to the protective factors of the host. Data on the persistence potential of H.pylori in accordance with the proposed classification are presented.
Zh. Mikrobiol. (Moscow), 2002, No. 2, P. 89—94