Kabardino-Balkar State University, Nalchik, Russia
In 41 patients aged 24—63 years with acute Flexner’s dysentery T-lymphocyte subpopulations CD-3, CD-4, CD-8, IRI and the content of tumor necrosis factor α (TNF-α) in the blood serum were detected. The suppression of T-cell mediated immunity on account of the presence of CD-4 with decreased immunoregulatory index and an increased content of TNF-α were established. Changes in T-cell mediated immunity and TNF-α depended on the period and the severity of the diseases.
Zh. Mikrobiol. (Moscow), 2004, No. 4, P. 72—74