Markina, O.A., Yasrebova, N.E., Vaneeva, N.P., Lyashova, V.N. Ovechko, N.N.

Cross-reactions between the antigens of healthy pulmonary tissue and Moraxella catarrhalis

Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia

The study of cross-reactions between healthy pulmonary tissue antigens and Moraxella catarrhalis with the use of SDS-electrophoresis and immunoblotting revealed that in the component of healthy pulmonary tissue with a mol. wt. of 40 kD epitopes existed to which antibodies were produced, capable of cross reaction with the components of M.catarrhalis with a mol. wt. of 35 kD and 70 kD. In addition, the presence of cross-reactions between cytokeratin-8, protein contained in healthy pulmonary tissue, and M.catarrhalis antigens was established.
Zh. Mikrobiol. (Moscow), 2004, No. 4, P. 40—43