State Medical Academy, State Regional Clinical Hospital, Novosibirsk, Russia
A total of 67 patients with blood system diseases and infectious complications were examined. During the period of the examination 139 microorganisms were isolated. Of these Gram negative microorganisms constituted 51%, Gram positive microorganisms — 34.8% and fungal flora — 14.2%. Most frequently the following Gram negative microorganisms were isolated from the patients: Pseudomonas sp. (including P.aeruginosa), Klebsiella pneumoniae, Escherichia coli, Haemophilus influenzae. All isolated microorganisms retained sensitivity to imipenem, with the exception of individual strains of Pseudomonas sp.; the latter exhibited sensitivity to amicacin and ceftazidim. Cefotaxime was active with respect to 75% of K.pneumoniae strains and all E.coli strains, ciprofloxacin was active with respect to 43% of E.coli strains, 80% of K.pneumoniae strains and 83.4% of Pseudomonas sp. strains, cefepim was active with respect to 85.7% of Pseudomonas sp. strains and all E.coli strains, ceftazidim was active with respect to all Pseudomonas sp. and E.coli strains. 75% of K.pneumoniae strains, 77.8% of Pseudomonas sp. strains and 86% of E.coli strains retained sensitivity to amicacin. 25% of K.pneumoniae strains required testing for ESBL production.
Zh. Mikrobiol. (Moscow), 2004, No. 3, P. 3—6