State Unitary Enterprise “Immunopreparat”, Ufa; Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia
Proteolytic enzyme produced by Bacillus subtilis is characterized as typical metalloprotease with a molecular weight of 27.9 kD; the enzyme shows its highest activity at pH 7.0—9.0, possesses substrate specificity with respect to different proteins, its temperature optimum is 52°C and its specific activity exceeds that of all known commercial analogues. At 37°C the enzyme is half inactivated in 72 hours.
Zh. Mikrobiol. (Moscow), 2003, No.3, P. 91—93