Gorbunov,S.G., Bondarenko,V.M., Demina,A.A., Spirikhina,L.V., Yastrebova,N.E., Vaneeva,N.P., Orlova,E.V., Tamazian,G.V., Zakharova,N.I.

Postvaccinal immunity and Haemophilus influenzae carrier state in children of different age groups after the administration of the vaccine “Act-HIB”

Central Research Institute of Epidemiology, Gamaleya Research Institute of Epidemiology and Microbiology, Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia

The article deals with H.influenzae (different serotypes) carrier state and immune response before and after the administration of the vaccine “Act-HIB” to children of different age groups. Children aged up to 1 year and over 1 year have been found to differ in the dynamics of carrier state and in the concentration of antibodies of different classes to the antigens of this infective agent, which makes it necessary to carry out their early immunization with a view to ensure their protection from H.influenzae infection.
Zh.Mikrobiol.(Moscow), 2003, No. 3, P. 27—30