Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia
Features of meningococcal carriage as a form of microorganism"s persistence necessary for survival and species preservation are discussed in this review. New data on genetic heterogeneity of meningococcal population, which is major determinant of occurrence of asymptomatic forms, are presented. Process of formation of meningococcal biofilms is described. Materials about systemic and local immunity developed during meningococcal carriage and possible influence of vaccination on carriage rate are reviewed. Role of persistence of meningococci in stimulation of immune protection of population from severe forms is discussed.
Zh. Mikrobiol. (Moscow), 2009, No. 4, P. 8—12