Rostov Research Institute of Microbiology and Parasitology; Clinical Diagnostic Center "Alyans", Rostov-on-Don, Russia
Aim. To study prevalence of hemolytic Escherichia in microbiocenosis of large intestine in 501 adult persons from Rostov-on-Don city. Materials and methods. Comparison of qualitative and quantitative composition of large intestine microbiocenosis in 248 persons with ultrasound examination of functional state of biliary tract was performed. Results. Statistically significant dependence of the rate of hemolytic Escherichia detection in microflora of large intestine from presence of dysfunctional disorders of biliary tract (biliary tract dysfunction) was revealed. Difference in character of microecological changes in large intestine of patients with such disorders and persons treated with wide-spectrum antibiotics was established. It was revealed that main feature of large intestine dysbiosis in patients with biliary tract dysfunction was the presence of significant quantity of hemolytic Escherichia as part of this compartment’s microflora. Conclusion. Hypothesis about possible role of functional disorders of biliary tract as a primary cause of microecologic imbalance was proposed.
Zh. Mikrobiol. (Moscow), 2009, No. 3, P. 89—92