Mechnikov Research Institute of Vaccines and Sera; Institute of Immunology, Moscow; Center for Control of HIV infection and AIDS, Kaliningrad, Russia
Course of postvaccinal period after injection of vaccine against Haemophilus influenzae type b administered simultaneously with vaccines of Russian national immunization schedule was studied in children born from HIV-infected mothers. Good tolerability of the vaccine administered concomitantly with diphtheria-tetanus-whole cell pertussis and inactivated polio vaccines (Imovax Polio), which is comparable with tolerability in healthy children, was demonstrated. Prevaccination titers of antibodies and their dynamics during immunization process were described. Increase of levels of antibodies was detected both in the group of children with perinatal contact with HIV infection and in the group of HIV-infected children.
Zh. Mikrobiol. (Moscow), 2008, No. 4, P. 50—55