Chumakov Institute of Poliomyelitis and Viral Encephalites; Ministry of Health of Moscow region; Hemotransfusion Station of Moscow region, Moscow, Russia
Assessment of immunity to poliomyelitis in adults from 8 towns of Moscow region was conducted. Low levels of population immunity against some serotypes of poliovirus in several towns have been found. At the same time, these levels were high and very high in other towns. Measurement of levels of strain-specific antibodies to vac-cine and wild polioviruses demonstrated wide circulation of wild polioviruses during past decades which had sig-nificant influence on formation of immunity. Substantial number of non-immune adults represents favorable condi-tions for circulation of vaccine polioviruses after cessation of vaccination, which, in its turn, could result in reestab-lishment of their neurovirulent properties and subsequent reemergence of poliomyelitis.
Zh. Mikrobiol. (Moscow), 2008, No. 1, P. 41—46