Bugorkova, S.A., Zadumina, S.Yu., Bugorkova, T.V., Lotsmanova, E.Yu., Kravtsov, A.L., Shchukovskaya, T.N., Kutyrev, V.V.

A complex morphological approach to assessment of protective properties of preparations for cholera specific prophylaxis

Russian Research Institute for Plague Control "Microbe", Saratov, Russia

Using developed scheme, complex study of protective properties of avirulent recombinant strain Vibrio chol-erae El Tor Inaba KM 184 was performed. Necessity for broadening of standard procedure of testing of cholera vaccines protective properties by using of quantitative methods of assessment of morphological changes and state of biomodel’s functional systems, which could increase the information value of assessment of studied vac-cines, was experimentally substantiated.
Zh. Mikrobiol. (Moscow), 2008, No. 1, P. 31—34