Dzagurova, T.K., Tkachenko, E.A., Yunicheva, Yu.V., Morozov, V.G., Bryukhanov, A.F., Bashkirtsev, V.N., Smir-nov, A.A., Sedova, N.S., Klempa, B., Kruger, D.

Discovery, clinical and etiological characteristic of hemorrhagic fever with renal syndrome in the subtropical zone of Krasnodar region

Chumakov Institute of Poliomyelitis and Viral Encephalites, Moscow; Station for Plaque Control, Sochi; Institute of Military Medi-cine, Samara, Russia; Institute of Virology, Berlin, Germany

Twenty-six patients with hemorrhagic fever with renal syndrome (HFRS) were revealed as a result of serologi-cal examination of 582 patients with fever living around Sochi town. Etiologic role of Dobrava virus subtype as the cause of HFRS was assessed by immunofluorescent and ELISA assays, and neutralization test. The principal host of this virus and source of infection for humans is Caucasian forest mouse Apodemus ponticus. HFRS mor-bidity was sporadic and not dependent from patients’ occupation and season. Comparative analysis of clinical and laboratory data from HFRS cases caused by DOB/Sochi and DOB/Lipetsk subspecies, as well as Puumala virus showed higher proportion of severe forms of disease in patients with HFRS from Sochi.
Zh. Mikrobiol. (Moscow), 2008, No. 1, P. 12—16

Dzagurova, T.K., Tkachenko, E.A., Yunicheva, Yu.V., Morozov, V.G., Bryukhanov, A.F., Bashkirtsev, V.N., Smir-nov, A.A., Sedova, N.S., Klempa, B., Kruger, D. Discovery, clinical and etiological characteristic of hemorrhagic fever with renal syndrome in the subtropical zone of Krasnodar region

Dzagurova, T.K., Tkachenko, E.A., Yunicheva, Yu.V., Morozov, V.G., Bryukhanov, A.F., Bashkirtsev, V.N., Smir-nov, A.A., Sedova, N.S., Klempa, B., Kruger, D.

Discovery, clinical and etiological characteristic of hemorrhagic fever with renal syndrome in the subtropical zone of Krasnodar region