Polyakov, A.E., Mazurova, I.K.

Direct nitrate reductase method of assessment of Mycobacterium tuberculosis susceptibility to drug

Gabrichevsky Research Institute of Epidemiology and Microbiology, Moscow, Russia

Microbiological method of direct accelerated assessment of resistance of Mycobacterium tuberculosis to rifam-picin and isoniazide was developed which is able to detect multidrug resistant M. tuberculosis 10 - 21 days after obtaining of sputum - 4 - 5 times faster compared with the method of absolute concentrations. Efficacy of the method was 0.93 and 0.96 during assessment of susceptibility to rifampicin and isoniazide respectively.
Zh. Microbiol. (Moscow), 2007, No. 5, P. 94—96