Kartashova, O.L., Kirgizova, S.B., Potekhina, L.P., Bukharin O.V.

Diagnostic value of persistent characteristics of staphylococci during their carriage

Institute of Cellular and Intracellular Symbiosis, Orenburg, Russia

Comparative assessment of information value of significant persistent characteristics of staphylococci in state of carriage was made, and the usefulness of these characteristics for creating diagnostic models was defined. One hundred and fifty strains of Staphylococcus aureus and S.åpidermidis isolated from healthy persons with subsequent differentiation of carriage types were used in the study. It has been established that strains isolated from resident carriers more often have more markedly expressed factors of persistence. Ranking the factors of persistence of staphylococci according to their information value during carriage allowed to identify the leading sign among them — anti-carnosine activity. Using factor analysis, obtained signs were united in the single com-plex defining bacterial carriage, which allows to build a mathematical model permitting to diagnose staphylococcal carriage with 95% probability.
Zh. Microbiol. (Moscow), 2007, No. 5, P. 13—16