Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia
Characteristics of new Bacillus subtilis isolates from the environment and had high antagonistic activity were studied. Absence of virulence and toxin production allows to regard them as potential probiotic cultures. Growth media for cultivation of B.subtilis were chosen according to the principle of individual adequacy in system, which give the ability to optimize processes of cultivation, obtaining of inhibitory substances and antagonistic activity spectrum determination.
Zh. Mikrobiol. (Moscow), 2007, No. 4, P. 41—46